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Understanding Prostate Diseases
Radiation Therapy
   
     
  Radiation therapy uses high-energy X-rays to kill cancer cells.1 Radiation is used most often for cancer that has not spread outside the prostate gland, or has spread only to nearby tissue.2 If the disease is more advanced, radiation may be used to shrink the tumor and provide symptomatic relief.3

What are possible side effects: Fatigue, bladder and/or rectal irritation, urine leakage, blood in the urine, impotence, or problems with bowel movements.4

Who makes a good candidate: Men who cannot or will not have their prostate removed, or men whose health makes his surgery risk higher than typical men. This procedure provides survival results equal to surgery for a man with a life expectancy of at least seven to 10 years.5

Two main types of radiation therapy are used to treat prostate cancer — external beam radiation and internal radiation. As always, discuss with your physician the therapy that is best for you.

External beam radiation therapy (EBRT) is a procedure where beams of high-energy radiation are focused from outside the body onto the targeted area.

Each treatment is an in-office procedure and lasts less than 15 minutes each day. Patients usually have five treatments per week at an outpatient center over a period of seven or eight weeks. With this procedure there is no risk of surgical bleeding, no hospitalization, usually no pain, no heart attacks, strokes, or blood clots.6

Internal radiation (also called brachytherapy) uses small radioactive pellets (each about the size of a grain of rice) implanted directly into the prostate through a thin needle.7 They may be permanent or temporary. The permanent pellets, which are sometimes called seeds, give off radiation for weeks or months.8 Because they are so small, they cause little discomfort and are simply left in place after their radioactive material is used.9

In another method, needles containing a higher amount of radioactive material can be used to place the material for less than a day.10 This approach is called high dose rate brachytherapy. With this procedure, you are usually required to stay in the hospital no longer than overnight, if that long. For about a week after the insertion of the needles, patients may have some pain in the area and a red-brown discoloration of their urine.11

 


References

Important Safety Considerations
Viadur should not be used by patients who are allergic to the drug leuprolide. Viadur should not be used by women or children and was not studied in women or children.
Viadur, like other similar medications, causes a temporary increase of testosterone in the blood during the first week of treatment. During this initial period, patients may experience worsening of symptoms or onset of new symptoms including bone pain, nervous system disturbances, blood in the urine, difficulty urinating, and spinal cord compression.
During treatment, the most common side effects reported throughout the body were hot flashes, lack of energy, breast enlargement, depression, and sweating. The most common side effects reported where the implant was inserted in the arm were bruising and burning.

See Your Healthcare Provider
Remember, your doctor or health care provider is the single best source of information regarding you and your health. Please consult your doctor if you have any questions about your health, your symptoms, or your medication.

This information does not take the place of your doctor’s advice or instructions but should help answer some of the questions you might have about prostate cancer therapies.


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Bayer HealthCare Pharmaceuticals
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© Copyright 2007 Bayer HealthCare Pharmaceuticals. Viadur is a trademark of ALZA Corporation under license to Bayer HealthCare Pharmaceuticals. DUROS® is a registered trademark of ALZA Corporation.

The information provided on Bayer products is only intended for the United States audience. Regulatory requirements, regulations, laws, and distribution of information about drug products may vary from country to country. Product names and indications (product uses) also may be different in different countries. The prescribing information provided here is based on United States labeling and may not be appropriate outside of the United States.