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Physician Support
Radiation Therapy
   
     
 

Viadur is indicated in the palliative treatment of advanced prostate cancer. Bayer is not responsible for, and does not endorse, any of the information found on this page.

Treatment Options

Chemotherapy
  Cryosurgery
  Hormone therapy
  Radiation therapy
  Radical prostatectomy
  Transurethral resection of the prostate (TURP)
  Watchful waiting

There are many treatments for prostate cancer. The best one for you depends on a number of factors. These include your age, your overall health, and the stage and grade of your cancer.

Be sure to discuss the possible benefits, risks and side effects with each option. The sections here outline some of the general risks and side effects. However, your doctor is the best source of information on your condition. Before you and your doctor select any treatment approach, risks and benefits should be thoroughly discussed.Take the time to research all of your treatment options. Consider getting a second opinion before making a final decision. The most common treatment options for prostate cancer include watchful waiting, radiation, and hormone therapy.

Radiation Therapy

Radiation therapy uses high-energy X-rays to kill cancer cells.1 Radiation is used most often for cancer that has not spread outside the prostate gland, or has spread only to nearby tissue.2 If the disease is more advanced, radiation may be used to shrink the tumor and provide symptomatic relief.3

What are possible side effects: Fatigue, bladder and/or rectal irritation, urine leakage, blood in the urine, impotence, or problems with bowel movements.4

Who makes a good candidate: Men who cannot or will not have their prostate removed, or men whose health makes his surgery risk higher than typical men. This procedure provides survival results equal to surgery for a man with a life expectancy of at least seven to 10 years.5

Two main types of radiation therapy are used to treat prostate cancer — external beam radiation and internal radiation. As always, discuss with your physician the therapy that is best for you.

External beam radiation therapy (EBRT) is a procedure where beams of high-energy radiation are focused from outside the body onto the targeted area.

Each treatment is an in-office procedure and lasts less than 15 minutes each day. Patients usually have five treatments per week at an outpatient center over a period of seven or eight weeks. With this procedure there is no risk of surgical bleeding, no hospitalization, usually no pain, no heart attacks, strokes, or blood clots.6

Internal radiation (also called brachytherapy) uses small radioactive pellets (each about the size of a grain of rice) implanted directly into the prostate through a thin needle.7 They may be permanent or temporary. The permanent pellets, which are sometimes called seeds, give off radiation for weeks or months.8 Because they are so small, they cause little discomfort and are simply left in place after their radioactive material is used.9

In another method, needles containing a higher amount of radioactive material can be used to place the material for less than a day.10 This approach is called high dose rate brachytherapy. With this procedure, you are usually required to stay in the hospital no longer than overnight, if that long. For about a week after the insertion of the needles, patients may have some pain in the area and a red-brown discoloration of their urine.11

Viadur is indicated in the palliative treatment of advanced prostate cancer.

 


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References

Important Safety Considerations
Viadur is contraindicated in patients with hypersensitivity to Gn-RH, Gn-RH agonist analogs, or any of the components in Viadur.

Viadur is contraindicated in women and pediatric patients and was not studied in women or children.

Viadur, like other LH-RH agonists, causes a transient increase in serum concentrations of testosterone during the first week of treatment. Patients may experience a worsening of symptoms or onset of new symptoms including bone pain, neuropathy, hematuria, or ureteral or bladder outlet obstruction, and spinal cord compression.

The most comment systemic side effects were hot flashes (67.9%), asthenia (7.6%), gynecomastia (6.9%), depression (5.3%), and sweating (5.3%). The most common local side effects were bruising (34.6%) and burning (5.6%).


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© Copyright 2007 Bayer HealthCare Pharmaceuticals. Viadur is a trademark of ALZA Corporation under license to Bayer HealthCare Pharmaceuticals. DUROS® is a registered trademark of ALZA Corporation.

The information provided on Bayer products is only intended for the United States audience. Regulatory requirements, regulations, laws, and distribution of information about drug products may vary from country to country. Product names and indications (product uses) also may be different in different countries. The prescribing information provided here is based on United States labeling and may not be appropriate outside of the United States.